<i id='F1C4C3B44B'><strike id='F1C4C3B44B'><tt id='F1C4C3B44B'><var date-time="710d86"></var><area dir="e2077d"></area><map lang="9715a6"></map><pre date-time="10338c" id='F1C4C3B44B'></pre></tt></strike></i> By Lisa J Hackett, Huw Nolan and Jo Coghlan* of 
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